Confounding and control
نویسنده
چکیده
This paper deals both with the issues of confounding and of control, as the definition of a confounding factor is far from universal and there exist different methodological approaches, ex ante and ex post, for controlling for a confounding factor. In the first section the paper compares some definitions of a confounder given in the demographic and epidemiological literature with the definition of a confounder as a common cause of both treatment/exposure and response/outcome. In the second section, the paper examines confounder control from the data collection viewpoint and recalls the stratification approach for ex post control. The paper finally raises the issue of controlling for a common cause or for intervening variables, focusing in particular on latent confounders. 1 Institute of Demography, University of Louvain (UCLouvain), Louvain-la-Neuve, Belgium. E-mail: [email protected] Wunsch: Confounding and control 98 http://www.demographic-research.org
منابع مشابه
Methodological issues of confounding in analytical epidemiologic studies
Background: Confounding can be thought of as mixing the effect of exposure on the risk of disease with a third factor which distorts the measure of association such as risk ratio or odds ratio. This bias arises because of complex functional relationship of confounder with both exposure and disease (outcome). In this article, we provided a conceptual framework review of confounding issues in epi...
متن کاملبررسی روش سناسی مطالعه مورد- متقاطع در اپیدمیولوژی
The case-crossover design was developed in the early 1990s to study the effects of transient, short-term exposures on the risk of acute events such as myocardial infarction. To estimate relative risk, the exposure frequency during a period just before outcome onset (hazard period) is compared with exposure frequency during control time(s) in that person rather than in a control. One or more "co...
متن کاملSleep Architecture in Patients With Primary Snoring and Obstructive Sleep Apnea
Introduction: This study aimed to investigate sleep architecture in patients with primary snoring and obstructive sleep apnea. Methods: In this study, we analyzed polysomnographic data of 391 clients who referred to Sleep Disorders Research Center (SDRS). These people were classified into three groups based on their Apnea-Hypopnea Index (AHI) and snoring; control, Primary Snoring (PS), and Obs...
متن کاملComparison of Fat Distribution Parameters between Individuals with and without Metabolic Syndrome
Abstract Objective: The aim of this study was to compare the body fat parameters in individuals with and without metabolic syndrome using an objective method. Materials and methods: This case-control study was performed in Tehran and consisted of 105 individuals with age range of 20 to 55 years. All participants were overweight and obese. NCEP ATP III criteria were used for identifying subjec...
متن کاملAssociation of Low Zinc Concentration and Hyperleptinemia with Overweight and Insulin Resistance in Polycystic Ovary Syndrome Women
Background and Objective: It has been reported that low concentration of zinc in serum is associated with insulin resistance (IR), also appears to be a relationship between insulin and leptin. In this study the possibility of increased leptin concentration and zinc deficiency was evaluated; in the following, their relationship with overweight and IR was investigated in women with polycystic ova...
متن کاملThe Control Outcome Calibration Approach for Causal Inference With Unobserved Confounding
Unobserved confounding can seldom be ruled out with certainty in nonexperimental studies. Negative controls are sometimes used in epidemiologic practice to detect the presence of unobserved confounding. An outcome is said to be a valid negative control variable to the extent that it is influenced by unobserved confounders of the exposure effects on the outcome in view, although not directly inf...
متن کامل